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عمومی::
حجم خون مغزی
Anesthetics that simultane- ously vasodilate the cerebral circulation cause increases in cerebral blood volume (CBV) with the potential to increase ICP.
It includes limited mention of the influences on autoregulation, CO2 responsiveness, and CBV.
Second, control and manipulation of CBF are central to the management of ICP because as CBF varies in response to vasoconstrictor- vasodilator influences, CBV varies with it.63 With respect to ICP, CBV is the more critical variable.
In the normal brain, CBV is approximately 5 mL/100 g of brain, and over a Paco2 range of approximately 25 to 70 mm Hg, CBV changes by approximately 0.049 mL/100 g for each 1 mm Hg change in Paco2.
In an adult brain weighing approxi- mately 1400 g, this change can amount to 20 mL in total CBV for a Paco2 range of 25 to 55 mm Hg.
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